MRC: Developmental pathway funding scheme

07/09/2023

08/11/2023

Apply for funding to develop and test novel therapeutics, medical devices, diagnostics and other interventions. You can apply for academically-led translational projects that aim to either: improve prevention, diagnosis, prognosis or treatment of significant health needs develop research tools that increase the efficiency of developing interventions All diseases and interventions are eligible for support. You can also address global health issues. Your project can start and finish at any stage on the developmental pathway from early development, through pre-clinical refinement and testing to early-phase clinical studies and trials (up to phase 2a). You can submit follow-on proposals where you can justify the need for continued support. There is no limit to the amount of funding you can apply for, or the length of your project. You should instead justify the timescale and resources needed in the context of the proposed work. Your project can start and finish at any stage on the developmental pathway from early development, through pre-clinical refinement and testing to early-phase clinical studies and trials (up to phase 2a). We usually fund 80% of a project’s full economic cost.

You can apply for funding for work on novel: - candidate therapeutic entities (for example, drug discovery) - vaccines for infectious or non-infectious disease - biologics (antibodies, peptides, proteins) - advanced therapeutics (for example, gene therapy and T-cell therapy) - regenerative medicine approaches - repurposing clinical studies or using existing therapies for new indications - medical devices - digital healthcare, app development or artificial intelligence - diagnostics (including biomarker validation) - medical imaging technology - surgical techniques or tools - behavioural and psychological interventions - radiotherapy and radiation protocols - interventions that benefit health in low and middle-income countries.

Eligibility Note To be eligible to apply for this funding opportunity you must: be a researcher employed by an eligible research organisation show that you will direct the project and be actively engaged in the work be looking to develop and test novel therapeutics, medical devices, diagnostics and other interventions International applicants You can include international co-investigators if they provide expertise not available in the UK. The inclusion of an international co-investigator must be discussed and agreed with the relevant programme manager before you submit the application to us.